Welcome

Welcome to my research page. I am a Postdoctoral Fellow at the Wellcome Trust Sanger Institute and a postdoctoral affiliate at Darwin College, Cambridge. I work in bioinformatics at the Genomics of Gene Regulation group with Daniel Gaffney. Click here for my webpage at the Sanger.

Background

I was an undergraduate at the University of Coimbra, where I studied Computer Science. Subsequently, I spent a year at the Centre for Earth Observation (ESRIN) of the European Space Agency (ESA), working on a toolbox for analysing remote sensing satellite data. Following my time at ESA, I trained with Alvis Brazma for a PhD in Molecular Biology at the European Bioinformatics Institute (EBI-EMBL) and the University of Cambridge. There I worked on computational methods for the analysis of RNA sequencing data and applied them to study the divergence of gene expression and isoform usage in mammals. In my current research, I am interested in uncovering genetic bases for the molecular and functional variability observed in human induced pluripotent stem cells.

Publications


Profile on google scholar.


Teaching

Lectures and practicals on RNA-Seq, Next Generation Sequencing, R and Bioconductor:

Next Generation Genomics 2014, University of Helsinki, Finland
Winter School on Analysis of Massively-Parallel Sequencing Data, NIBMG, Kalyani, India
Next Generation Genomics Data Analysis Workshop, C-CAMP, Bangalore, India
RNA Biology Module of the EMBL Predoc Course EMBL, Heidelberg, Germany
Next Generation Genomics 2012, University of Helsinki, Finland
Advanced RNA-Seq and Chip-Seq Data Analysis Course, EMBL-EBI, Cambridge, UK
ENGAGE RNA-seq Course, EMBL-EBI, Cambridge, UK
EMBO Course on Analysis and Informatics of Transcriptomics Data, EMBL-EBI, Cambridge, UK
Next-generation Sequencing for Biomedical Omics (iDSDn2010), Castel Ivano, Ivano Fracena, Italy
13th InternationalMGED Meeting, Boston, Massachusetts, USA

Laboratory demonstrator Department of Informatics Engineering, University of Coimbra, Portugal:

Undergraduate-level course “Introduction to Programming”
Undergraduate-level course “Computation Theory”
Graduate-level course “Artificial Intelligence”